IRF4, interferon regulatory factor 4, 3662

N. diseases: 203; N. variants: 10
Disease: Asthma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004096
Disease: Asthma
Asthma 		0.130 GeneticVariation disease GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738 2019
CUI: C0004096
Disease: Asthma
Asthma 		0.130 GeneticVariation disease BEFREE The IRF-4 variant rs9378805 was associated with recurrent bronchitis in the ISAAC population and replicated in the GWAS data set where further SNPs showed associations with recurrent bronchitis and asthma. 24074333 2013
CUI: C0004096
Disease: Asthma
Asthma 		0.130 AlteredExpression disease BEFREE The levels of IRF4 were elevated in allergic asthmatics compared with those in healthy controls. 22515488 2012
CUI: C0004096
Disease: Asthma
Asthma 		0.130 Biomarker disease BEFREE Our data clearly demonstrate the central function of IRF4 in the development of Th9 cells and underline the contribution of this T helper cell subset to the pathogenesis of asthma. 20674401 2010