IRF4, interferon regulatory factor 4, 3662

N. diseases: 203; N. variants: 10
Disease: Squamous cell carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.110 GeneticVariation disease GWASCAT Combined analysis of keratinocyte cancers identifies novel genome-wide loci. 31174203 2019
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.110 GeneticVariation disease GWASCAT Identification of Susceptibility Loci for Cutaneous Squamous Cell Carcinoma. 26829030 2016
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.110 GeneticVariation disease BEFREE Along with two known pigmentation loci, MC1R and OCA2, the IRF4 rs12203592 T allele was associated with an increased risk of each type of skin cancer (P value, 6.6 × 10(-4) for melanoma, 7.0 × 10(-7) for SCC, and 0.04 for BCC). 21270109 2011