IRF4, interferon regulatory factor 4, 3662

N. diseases: 203; N. variants: 10
Disease: Gonorrhea ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018081
Disease: Gonorrhea
Gonorrhea 		0.040 AlteredExpression disease BEFREE The four cases with FISH-detectable abnormalities showed MUM1 expression and had a non-germinal center (GC) phenotype. 21752100 2011
CUI: C0018081
Disease: Gonorrhea
Gonorrhea 		0.040 Biomarker disease BEFREE All PTLD with clonal Ig rearrangements showed evidence of germinal centre (GC) transit based on the analysis of Ig and BCL6 gene mutations, and 74% had a non-GC phenotype (BCL6 +/- MUM1+). 18457340 2008
CUI: C0018081
Disease: Gonorrhea
Gonorrhea 		0.040 AlteredExpression disease BEFREE EBV positivity was associated with MUM-1/IRF4 expression (P=0.005) and with a non-GC phenotype (P=0.01).All CD138 cases were EBV. 17122518 2006
CUI: C0018081
Disease: Gonorrhea
Gonorrhea 		0.040 Biomarker disease BEFREE Histogenetic B cell marker studies, available in 13 cases, showed an early post-germinal center (GC) phenotype (BCL-6(-)/IRF4(+)/CD138(-)) (n=5) or a late post-GC phenotype (BCL-6(-)/IRF4(+)/CD138(+)) (n=8), which could be helpful for discrimination from other types of small-B cell lymphoma. 16323006 2006