IRF7, interferon regulatory factor 7, 3665

N. diseases: 121; N. variants: 11
Disease: Autoimmune Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.020 Biomarker group BEFREE IRF7 activation is tightly regulated to prevent excessive inflammation and autoimmunity; however, how IRF7 is suppressed by negative regulators remains poorly understood. 25911105 2015
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.020 GeneticVariation group BEFREE The results show that variation in the IRF7 genomic region is associated with the presence of ACA in patients with SSc, supporting other evidence that this locus represents a common risk factor for autoantibody production in autoimmune diseases. 21926187 2012