IRF7, interferon regulatory factor 7, 3665

N. diseases: 121; N. variants: 11
Disease: Glioma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma 		0.020 AlteredExpression disease BEFREE In an in vitro invasion assay, IRF7 overexpression enhanced glioma cell invasion. 25680411 2015
CUI: C0017638
Disease: Glioma
Glioma 		0.020 Biomarker disease BEFREE Taken together, our findings indicate that interferon regulatory factor 7-mediated inflammatory signalling acts as a major driver of brain tumour progression and cellular heterogeneity via induction of glioma stem cell genesis and angiogenesis. 22434214 2012