IRF7, interferon regulatory factor 7, 3665

N. diseases: 121; N. variants: 11
Disease: Breast Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.020 AlteredExpression disease BEFREE These findings establish chemotherapy-induced immunological dormancy in ER<sup>-</sup> breast cancer as a novel concept for (neo)adjuvant chemotherapy activity, and implicate sustained activation of the IRF7/IFN-β/IFNAR pathway in this effect. 30546090 2019
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.020 Biomarker disease BEFREE Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape. 22820642 2012