ISL1, ISL LIM homeobox 1, 3670

N. diseases: 94; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.040 Biomarker group BEFREE ISL1, a novel regulator of CCNB1, CCNB2 and c-MYC genes, promotes gastric cancer cell proliferation and tumor growth. 27183908 2016
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.040 Biomarker group BEFREE However, how ISL-1 exerts the role in tumor development is not clear. 25070240 2014
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.040 Biomarker group BEFREE Recent studies indicate that ISL-1 may also involve in the occurrence of a variety of tumors. 24845569 2014
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.040 GeneticVariation group BEFREE We examined the mRNA expression of C terminus-binding protein-interacting protein and Lin11, Isl-1, and Mec-3 domain only 4 (LMO4) in pretreatment tumor samples from 91 erlotinib-treated advanced non-small-cell lung cancer patients with EGFR mutations in whom breast cancer gene 1 (BRCA1) expression and the concomitant presence of the EGFR T790M mutation had previously been assessed. 23407556 2013