ITGAE, integrin subunit alpha E, 3682

N. diseases: 95; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1368683
Disease: Epithelioma
Epithelioma
0.020 Biomarker disease BEFREE Here, we used viable human lung tumor slices and autologous tumor antigen-specific T-lymphocyte clones to provide evidence that CD103 is directly involved in T-lymphocyte recruitment within epithelial tumor islets and intratumoral early T-cell signaling. 26921343 2016
CUI: C1368683
Disease: Epithelioma
Epithelioma
0.020 Biomarker disease BEFREE We had previously demonstrated the role of CD103 integrin on lung tumor-infiltrating lymphocyte (TIL) clones in promoting specific TCR-mediated epithelial tumor cell cytotoxicity. 25725111 2015