ITGAX, integrin subunit alpha X, 3687

N. diseases: 170; N. variants: 8
Disease: Hairy Cell Leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023443
Disease: Hairy Cell Leukemia
Hairy Cell Leukemia 		0.080 AlteredExpression disease BEFREE CD11c, expressed not only in Hairy cell leukemia but also in dendritic cells, macrophages and monocytes is a differentiation marker for inflammation. 28603911 2017
CUI: C0023443
Disease: Hairy Cell Leukemia
Hairy Cell Leukemia 		0.080 Biomarker disease LHGDN We recommend that this CD11c antibody be added to a panel of antibodies for immunostaining of formalin-fixed material, for differentiation of HCL from other small B-cell lymphomas, and for detection of residual disease following therapy. 18580071 2008
CUI: C0023443
Disease: Hairy Cell Leukemia
Hairy Cell Leukemia 		0.080 AlteredExpression disease BEFREE In order to determine the cause of CD11c gene expression in HCL the CD11c gene promoter was characterized. 12576324 2003
CUI: C0023443
Disease: Hairy Cell Leukemia
Hairy Cell Leukemia 		0.080 AlteredExpression disease LHGDN In order to determine the cause of CD11c gene expression in HCL the CD11c gene promoter was characterized. 12576324 2003
CUI: C0023443
Disease: Hairy Cell Leukemia
Hairy Cell Leukemia 		0.080 AlteredExpression disease BEFREE CD11c/CD18 is expressed primarily on cells of the myeloid lineage and activated B lymphocytes, and is an important diagnostic marker for hairy cell leukemia. 8621914 1996
CUI: C0023443
Disease: Hairy Cell Leukemia
Hairy Cell Leukemia 		0.080 Biomarker disease BEFREE In addition, the cells expressed CD11c recognized by Leu-M5, a monoclonal antibody usually positive for HCL. 7985490 1994
CUI: C0023443
Disease: Hairy Cell Leukemia
Hairy Cell Leukemia 		0.080 Biomarker disease BEFREE Our findings suggest that CD11c+CD5+ B-cell leukemias with atypical morphologic features represent forms of CLL or PLL rather than HCL. 1694698 1990
CUI: C0023443
Disease: Hairy Cell Leukemia
Hairy Cell Leukemia 		0.080 Biomarker disease BEFREE Hairy cell leukemia-associated antigen LeuM5 (CD11c) is preferentially expressed by benign activated and neoplastic CD8 T cells. 2105060 1990
CUI: C0023443
Disease: Hairy Cell Leukemia
Hairy Cell Leukemia 		0.080 Biomarker disease BEFREE The BNBH-I cells possessed the antigen recognized by Leu-M5, a highly specific MAb for HCL. 3391709 1988