ITGB1, integrin subunit beta 1, 3688
N. diseases: 210; N. variants: 4
Source: ALL
| Disease | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | AlteredExpression | disease | BEFREE | To evaluate clinical relevance, we examined these genes in a human public dataset and found that ITGB1 and KRT6B expression in BC patient tumor samples are positively correlated with tumor grade. | 31092844 | 2019 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | The expression levels of ITGB1 and microRNA-10a in BCa tissues were negatively correlated. | 31486485 | 2019 | ||||
|
0.070 | Biomarker | disease | BEFREE | Since integrin β1 is frequently upregulated in chemoresistant urothelial cancer cell lines and inhibition of integrin β1 may influence adhesion, further studies are warranted to evaluate integrin β1 as a potential therapeutic target for bladder cancer <i>in vivo</i>. | 29113179 | 2017 | ||||
|
0.070 | Biomarker | disease | BEFREE | Our findings suggest that the miR-130b-3p/PTEN/integrin β1 axis could play a critical role in the progression and development of BC and that miR-130b-3p might be a valuable clinical marker and therapeutical target for BC patients. | 28042869 | 2016 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | The expression of integrinβ1 on bladder cancer T24 and 5637 cells was examined by the flow cytometer. | 22386417 | 2012 | ||||
|
0.070 | Biomarker | disease | LHGDN | "A specific microdomain (""glycosynapse 3"") controls phenotypic conversion and reversion of bladder cancer cells through GM3-mediated interaction of alpha3beta1 integrin with CD9." | 16103120 | 2005 | ||||
|
0.070 | AlteredExpression | disease | LHGDN | Expression of beta1-integrins and N-cadherin in bladder cancer and melanoma cell lines. | 11996105 | 2000 |