ITGB1, integrin subunit beta 1, 3688

N. diseases: 210; N. variants: 4
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.080 AlteredExpression disease BEFREE We focused on integrin β1, which is the most highly expressed integrin in our cohort of uveal melanomas. 28284838 2017
CUI: C0025202
Disease: melanoma
melanoma 		0.080 AlteredExpression disease BEFREE Biglycan expression in the melanoma microenvironment promotes invasiveness via increased tissue stiffness inducing integrin-β1 expression. 28476030 2017
CUI: C0025202
Disease: melanoma
melanoma 		0.080 Biomarker disease LHGDN Integrin VLA-4 enhances sialyl-Lewisx/a-negative melanoma adhesion to and extravasation through the endothelium under low flow conditions. 18632734 2008
CUI: C0025202
Disease: melanoma
melanoma 		0.080 AlteredExpression disease LHGDN High affinity interaction of integrin alpha4beta1 (VLA-4) and vascular cell adhesion molecule 1 (VCAM-1) enhances migration of human melanoma cells across activated endothelial cell layers. 17352405 2007
CUI: C0025202
Disease: melanoma
melanoma 		0.080 Biomarker disease LHGDN Differential modulation of human melanoma cell metalloproteinase expression by alpha2beta1 integrin and CD44 triple-helical ligands derived from type IV collagen. 15292257 2004
CUI: C0025202
Disease: melanoma
melanoma 		0.080 AlteredExpression disease LHGDN Molecular proximity of seprase and the urokinase-type plasminogen activator receptor on malignant melanoma cell membranes: dependence on beta1 integrins and the cytoskeleton. 12376466 2002
CUI: C0025202
Disease: melanoma
melanoma 		0.080 Biomarker disease LHGDN Regulation of integrin function by CD47 ligands. Differential effects on alpha vbeta 3 and alpha 4beta1 integrin-mediated adhesion. 12218055 2002
CUI: C0025202
Disease: melanoma
melanoma 		0.080 AlteredExpression disease LHGDN Expression of beta1-integrins and N-cadherin in bladder cancer and melanoma cell lines. 11996105 2000