ITGB1, integrin subunit beta 1, 3688

N. diseases: 210; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.050 Biomarker group LHGDN Functional live-cell imaging demonstrates that beta1-integrin promotes type IV collagen degradation by breast and prostate cancer cells. 19123990 2009
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.050 Biomarker group LHGDN Osteoblasts-derived BMP-2 enhances the motility of prostate cancer cells via activation of integrins. 18512729 2008
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.050 Biomarker group LHGDN Hierarchical organization of prostate cancer cells in xenograft tumors: the CD44+alpha2beta1+ cell population is enriched in tumor-initiating cells. 17638891 2007
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.050 AlteredExpression group LHGDN Metastatic properties of prostate cancer cells are controlled by VEGF. 15500293 2005
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.050 Biomarker group LHGDN Bombesin-dependent pro-MMP-9 activation in prostatic cancer cells requires beta1 integrin engagement. 12372334 2002