ITGB2, integrin subunit beta 2, 3689

N. diseases: 340; N. variants: 31
Disease: Carney Complex ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0406810
Disease: Carney Complex
Carney Complex 		0.010 Biomarker disease BEFREE The carCTL immune synapse lacked distinct LFA-1 adhesion rings and was less reliant on LFA to form stable conjugates with target cells. carCTL receptors associated with the synapse were found to be disrupted and formed a convoluted multifocal pattern of Lck microclusters. 29440406 2018