ITGB2, integrin subunit beta 2, 3689

N. diseases: 340; N. variants: 31
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1332206
Disease: Adult Lymphoma
Adult Lymphoma
0.030 Biomarker disease BEFREE Accordingly, we developed a lymphoma progression model comprising cell lines established at indolent (MAC-1) and aggressive (MAC-2A) CTCL stages. 27144517 2016
CUI: C1332206
Disease: Adult Lymphoma
Adult Lymphoma
0.030 Biomarker disease BEFREE Mac-2A cells, clonally related to Mac-1 and isolated from a skin nodule of the same patient at a later, clinically aggressive stage of lymphoma, are resistant to TGF-beta. 8668164 1996
CUI: C1332206
Disease: Adult Lymphoma
Adult Lymphoma
0.030 GeneticVariation disease BEFREE Three clonally related lymphoma lines (Mac-1, Mac-2A and Mac-2B) derived from progressive stages of CD30+ cutaneous T-cell lymphoma were found to constitutively secrete GM-CSF. 9162223 1996