ITK, IL2 inducible T cell kinase, 3702

N. diseases: 117; N. variants: 12
Disease: B-Cell Lymphomas ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0079731
Disease: B-Cell Lymphomas
B-Cell Lymphomas 		0.020 Biomarker group BEFREE Ibrutinib, BTK, and ITK irreversible inhibitor is a FDA-approved small molecule for the clinical therapy of B cell lymphoma. 29532266 2018
CUI: C0079731
Disease: B-Cell Lymphomas
B-Cell Lymphomas 		0.020 Biomarker group BEFREE Peripheral B-cell lymphomas were consistently negative for ITK, with occasional cases showing expression of DOK2 and SKAP55, and a proportion (47%) of hairy cell leukemias were GADS. 25118816 2014