ITK, IL2 inducible T cell kinase, 3702

N. diseases: 117; N. variants: 12
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.030 Biomarker disease BEFREE Targeting circFoxo3/Foxo3/EMT may provide an applicable strategy for exploring potential prognostic and therapeutic approaches for prostate cancer. 31593800 2020
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.030 Biomarker disease BEFREE These results contribute to insights into the metastatic mechanisms of EMT-PCBSLCs in PCa. 31122254 2019
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.030 Biomarker disease BEFREE Here we found that ASC-J9<sup>®</sup> could suppress PCa cell invasion via inducing the sumoylation of STAT3, thereby inhibiting the STAT3 phosphorylation that led to suppress the EMT-SNAIL2 signals in both PCa DU145 and PC3 AR-negative cells. 29425687 2018