JAK1, Janus kinase 1, 3716

N. diseases: 239; N. variants: 41
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.010 Biomarker disease BEFREE A limited decrease in neutrophils without neutropenia was consistent with immunomodulatory effects through JAK-1 inhibition.There were no infections.Overall, filgotinib was well tolerated. 28622463 2017