JAK1, Janus kinase 1, 3716

N. diseases: 239; N. variants: 41
Disease: Breast implant-associated anaplastic large cell lymphoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4528210
Disease: Breast implant-associated anaplastic large cell lymphoma
Breast implant-associated anaplastic large cell lymphoma 		0.010 GeneticVariation disease BEFREE However, the JAK-STAT3 pathway is constitutively activated in BIA-ALCL, which in some cases is associated with recurrent somatic mutations of JAK1 and/or STAT3. 30715169 2019