JAK2, Janus kinase 2, 3717

N. diseases: 644; N. variants: 54
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032109
Disease: Plasma cell mastitis
Plasma cell mastitis
0.020 Biomarker disease BEFREE Collectively, our results suggested that SH could inhibit the progression of PCM by suppressing IL-6/JAK2/STAT3 cascades and ultimately achieve a therapeutic effect in PCM. 31810886 2020
CUI: C0032109
Disease: Plasma cell mastitis
Plasma cell mastitis
0.020 AlteredExpression disease BEFREE Furthermore, treatment with AG-490, an inhibitor of JAK family kinases, suppressed activation of the IL-6/JAK2/STAT3 signaling cascade, in turn resulting in a decreased number of plasma cells in the mammary gland and reversing the pathogenesis of PCM. 29751177 2018