Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023827
Disease: liposarcoma
liposarcoma
0.010 Biomarker disease BEFREE Of particular interest, amplicons containing genes involved in the c-jun NH2-terminal kinase/mitogen-activated protein kinase pathway, that is, JUN in 1p32 and MAP3K7IP2 (TAB2) in 6q24-25, were found to be independently amplified in eight of 11 cases with 12q amplification, providing strong support for the notion that aberrant expression of this pathway is an important step in the dedifferentiation of liposarcomas. 16732325 2006