Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.100 Biomarker disease BEFREE In the BC group, NMP22 (p = 0.005) concentration, GST-π (p = 0.003) in urine and GST (p = 0.009) activity in blood were statistically significantly higher than in the healthy controls. 29211353 2017
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.100 GeneticVariation disease BEFREE We examined the association of common GST polymorphisms and bladder cancer (BC) risk in individuals from BEN areas in Serbia. 27568660 2016
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.100 GeneticVariation disease BEFREE We aimed to investigate bladder cancer risk with reference to polymorphic variants of cytochrome p450 (CYP) 1A1, CYP1B1, glutathione S-transferase (GST) M1, and GSTT1 genes in a case control study. 23886208 2013
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.100 GeneticVariation disease BEFREE Although polymorphisms in glutathione S-transferase (GST) have been associated with the risk of bladder cancer (BC) development, few reports provide information about the prognosis of BC. 21286014 2011
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.100 GeneticVariation disease BEFREE Although polymorphisms in glutathione S-transferase (GST) have been associated with the risk of bladder cancer (BC), few reports provide information about the development of BC. 21045267 2010
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.100 Biomarker disease BEFREE The lower most GST enzyme concentration was reported in patients with bilharzial bladder cancer (26 +/- 4.4 ng/ml) with significant difference between it and that of the second group (36.8 +/- 4.1 ng/ml, P < 0.05) and that of the controls (40.4 +/- 4 ng/ml, P < 0.005). 19117770 2010
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.100 GeneticVariation disease BEFREE To explore the association of polymorphisms in N-acetyltransferase 2 (NAT2), glutathione S-transferase (GST), cytochrome P450 (CYP) 2A6, and CYP 2A13 genes with susceptibility and clinicopathologic characteristics of bladder cancer in a Chinese population. 19303722 2009
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.100 GeneticVariation disease BEFREE The associations between the genotypes of glutathione S-transferase (GST) M1, GSTP1, GSTT1 and N-acetyltransferase (NAT) 1 and the phenotypes of NAT2 and cytochrome P450 (CYP) 1A2 and bladder cancer risk were examined in a case-control study involving 731 bladder cancer patients and 740 control subjects in Los Angeles County, California. 18544563 2008
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.100 GeneticVariation disease BEFREE These results suggest that polymorphisms in the GST genes are associated with increased risk of bladder cancer among Egyptians. 15832776 2005
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.100 GeneticVariation disease BEFREE We examined the association of the GST gene polymorphism with sporadic bladder cancer patients in Northern India. 16005379 2005
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.100 Biomarker disease BEFREE We investigated the role of glutathione S-transferase (GST) enzymes (M1, T1), methylenetetrahydrofolate (MTHFR) 677 and 1298, and the NAD(P)H:quinone oxidoreductase (NQO1) polymorphisms in a population-based bladder cancer case-control study in Argentina. 15219943 2004
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.100 GeneticVariation disease BEFREE Bladder cancer is associated with smoking, occupational exposures, and glutathione S-transferase (GST) M1 and N-acetyltransferase (NAT) 2 polymorphisms that may influence carcinogen metabolism, but somatic p53mutations are often CpG dinucleotide G:C-A:T transitions that can occur spontaneously. 14612556 2003
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.100 GeneticVariation disease BEFREE Glutathione S-transferase (GST) M1 polymorphism is a marker for susceptibility to smoking-related neoplasms, such as lung and bladder cancer. 10616169 1999
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.100 GeneticVariation disease BEFREE Defective glutathione S-transferase (GST) and N-acetyltransferase (NAT) enzymes have been associated with an increased risk of developing lung and bladder cancer. 7607565 1995