KARS1, lysyl-tRNA synthetase 1, 3735

N. diseases: 62; N. variants: 13
Disease: Cryptosporidiosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010418
Disease: Cryptosporidiosis
Cryptosporidiosis 		0.010 Biomarker disease BEFREE This series of compounds inhibit <i>Cp</i>KRS and <i>C. parvum</i> and <i>Cryptosporidium hominis</i> in culture, and our lead compound shows oral efficacy in two cryptosporidiosis mouse models. 30894487 2019