AREG, amphiregulin, 374

N. diseases: 221; N. variants: 0
Disease: Dermatologic disorders ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0037274
Disease: Dermatologic disorders
Dermatologic disorders 		0.040 Biomarker group BEFREE The epidermal growth factor (EGF)-receptor ligand amphiregulin (AREG) is a potent growth factor implicated in proliferative skin diseases and in primary and metastatic epithelial cancers. 29632822 2018
CUI: C0037274
Disease: Dermatologic disorders
Dermatologic disorders 		0.040 Biomarker group BEFREE Genetic deletion of amphiregulin restores the normal skin phenotype in a mouse model of the human skin disease tylosis. 28655741 2017
CUI: C0037274
Disease: Dermatologic disorders
Dermatologic disorders 		0.040 AlteredExpression group BEFREE Pharmacologic regulation of amphiregulin's expression and receptor signaling may eventually prove to be an effective strategy in the treatment of hyperproliferative skin diseases. 9804327 1998
CUI: C0037274
Disease: Dermatologic disorders
Dermatologic disorders 		0.040 AlteredExpression group BEFREE Overexpression of amphiregulin, a major autocrine growth factor for cultured human keratinocytes, in hyperproliferative skin diseases. 8739992 1996