Disease: Hypertensive disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.240 GeneticVariation group BEFREE The KCNQ1 rs3864884 and rs12576239 genetic variants were associated with hypertension in T2DM. 28059450 2017
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.240 GeneticVariation group BEFREE Therefore, our data support that KCNQ1 is associated with an increased risk for T2DM and might contribute to the higher incidence of hypertension and macrovascular complications in patients with T2DM carrying the risk allele C though it needs further to be confirmed in a larger population. 26678516 2015
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.240 GeneticVariation group BEFREE Five single nucleotide polymorphisms (SNPs) near the protein tyrosine phosphatase, receptor type, D (PTPRD), SRR, MAF/WWOX, and KCNQ1 genes were genotyped in 1138 subjects of Chinese origin from the Stanford Asia-Pacific Program for Hypertension and Insulin Resistance study. 21767287 2012
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.240 GeneticVariation group BEFREE One missense KCNQ1 mutation, R14C, was identified in 1 family with a high prevalence of hypertension. 17276182 2007
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.240 Biomarker group RGD Surprisingly, WTC-dfk rats showed hypertension, which suggested that Kcnq1 might be involved in the regulation of blood pressure. 16368876 2006