Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity
0.040 PosttranslationalModification disease BEFREE Obesity and ischemic stroke modulate the methylation levels of KCNQ1 in white blood cells. 25429063 2015
CUI: C0028754
Disease: Obesity
Obesity
0.040 Biomarker disease BEFREE Differential methylation is found within genes associated with obesity, epigenetic regulation and development, such as CETP, FOXP2, HDAC4, DNMT3B, KCNQ1 and HOX clusters. 25651499 2015
CUI: C0028754
Disease: Obesity
Obesity
0.040 GeneticVariation disease BEFREE Moreover, 18 obesity and 21 type 2 diabetes candidate genes had CpG sites with differences in adipose tissue DNA methylation in response to exercise (q<0.05), including TCF7L2 (6 CpG sites) and KCNQ1 (10 CpG sites). 23825961 2013
CUI: C0028754
Disease: Obesity
Obesity
0.040 Biomarker disease BEFREE Our findings indicate that KCNQ1 is associated with obesity in Chinese patients with type 2 diabetes. 22790062 2012