Glioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
RNA binding protein immunoprecipitation (RIP) assays demonstrated that metastasis associated lung adenocarcinoma transcript 1 (MALAT1), SOX2 overlapping transcript (SOX2OT) and maternally expressed 3 (MEG3) among the 8 candidates bound to the NSPc1 protein complex in glioma H4 cells.
|
30720120 |
2019 |
Glioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
The effects of MALAT1 and miR-129 on glioma tumour growth were further confirmed using xenograft mouse model.
|
29808528 |
2018 |
Glioma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
In the prognostic meta-analysis, high metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) expression could predict poor overall survival (OS) in patients with glioma, with a pooled HR of 2.32 (95% CI: 1.64-3.27, P < 0.001).
|
29777909 |
2018 |
Glioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
We further investigated the molecular mechanisms whereby Malat1 functioned on glioma cell autophagy and proliferation.
|
28834690 |
2017 |
Glioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Here, we aimed to elucidate the function and the possible molecular mechanisms of lncRNA Metastasis-associated lung Adenocarcinoma transcript-1 (MALAT1) in human glioma.
|
28551849 |
2017 |
Glioma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Dysregulation of MALAT1 expression is frequently observed in many types of cancer such as gastric cancer, esophageal squamous cell carcinoma and glioma.
|
28260102 |
2017 |
Glioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
MALAT1 decreased the sensitivity of resistant glioma cell lines to TMZ by regulating ZEB1.
|
28668966 |
2017 |
Glioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
In conclusion, overall data demonstrated the tumor-suppressive role of MALAT1 in glioma by attenuating ERK/MAPK-mediated growth and MMP2-mediated invasiveness.
|
26938295 |
2016 |
Glioma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Our results proved that MALAT1 expression was up-regulated in brain microvessels of human glioma and glioma endothelial cells (GECs) which were obtained by co-culturing endothelial cells with glioma cells.
|
26619802 |
2016 |
Glioma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
In this study, we aimed to identify the effects of MALAT1 on proliferation and the expression of stemness markers on glioma stem cell line SHG139S.
|
26649728 |
2016 |
Glioma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
In the present study, we explored the expression level of lncRNA MALAT1 in primary glioma tissues as well as in U87 and U251 glioma cell lines.
|
27134488 |
2016 |
Glioma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Multivariate analysis suggested that increased lncRNA MALAT1 expression was a poor independent prognostic predictor for glioma patients (P = 0.002).
|
25613066 |
2015 |