|
cervical cancer
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, we found that the periostin expression was positively correlated with the expression of metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), and negatively correlated with the expression of microRNA (miR)-202-3p in CC tissues.
|
30633360 |
2019 |
|
cervical cancer
|
0.100 |
Biomarker
|
disease |
BEFREE |
These findings revealed that MALAT1 can sponge miR-429 and regulate cervical cancer pathogenesis in vivo and in vitro.
|
30515786 |
2019 |
|
cervical cancer
|
0.100 |
Biomarker
|
disease |
BEFREE |
MALAT1 promoted the cisplatin resistance of cervical cancer, which might be related to regulation of cell apoptosis via BRWD1 and PI3K/AKT pathway.
|
30536307 |
2018 |
|
cervical cancer
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Disordered expression of MALAT1 has been observed in several cancers, including cervical cancer, breast cancer, and ovarian cancer.
|
28031721 |
2017 |
|
cervical cancer
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Here, we analyzed the expression of miRNA-143 and MALAT1 in HeLa cells to evaluate their roles in the occurrence and metastasis of cervical cancer.
|
28252165 |
2017 |
|
cervical cancer
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
We found higher expression of MALAT-1 in all the 4 CC cell lines, especially in SiHa and ME-180 CC cell lines.
|
26854446 |
2016 |
|
cervical cancer
|
0.100 |
Biomarker
|
disease |
BEFREE |
This study explored the role of MALAT1 in radiosensitivity of high-risk human papillomavirus (HR-HPV)-positive cervical cancer and whether there is a ceRNA mechanism which participated in its regulation over radiosensitivity.
|
26311052 |
2016 |
|
cervical cancer
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Findings of this study confirmed higher MALAT1 expression in HR-HPV (+) cervical cancer.
|
26242259 |
2016 |
|
cervical cancer
|
0.100 |
Biomarker
|
disease |
BEFREE |
Taken together, these results suggest that MALAT1 functions to promote cervical cancer invasion and metastasis via induction of EMT, and it may be a target for the prevention and therapy of cervical cancers.
|
26798987 |
2016 |
|
cervical cancer
|
0.100 |
Biomarker
|
disease |
BEFREE |
LncRNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) has recently been identified to be involved in tumorigenesis of several cancers such as lung cancer, pancreatic cancer, and cervical cancer.
|
25480417 |
2015 |
|
cervical cancer
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
MALAT1 expression is correlated with tumor size, FIGO stage, vascular invasion and lymph nodes metastasis and is an independent predictor for overall survival of cervical cancer.
|
26400521 |
2015 |
|
cervical cancer
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our findings illustrate the biological significance of MALAT1 in cervical cancer progression and provide novel evidence that MALAT1 may serve as a therapeutic target in the prevention of human cervical cancer.
|
20213048 |
2010 |