KDR, kinase insert domain receptor, 3791

N. diseases: 623; N. variants: 23
Disease: Astrocytoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004114
Disease: Astrocytoma
Astrocytoma 		0.050 Biomarker disease BEFREE Our results indicate that VEGFR2/TAZ signaling pathway plays an important role in angiogenesis in astrocytomas. 30615171 2019
CUI: C0004114
Disease: Astrocytoma
Astrocytoma 		0.050 GeneticVariation disease BEFREE Further studies about ethnically diverse populations with larger sample size should be performed to confirm the correlation between KDR gene polymorphisms and risk of astrocytomas. 26081139 2016
CUI: C0004114
Disease: Astrocytoma
Astrocytoma 		0.050 AlteredExpression disease BEFREE Interestingly, for the astrocytic gliomas, the expression of VEGFR correlated well to the tumor malignancy, even better than VEGF content. 15949234 2005
CUI: C0004114
Disease: Astrocytoma
Astrocytoma 		0.050 Biomarker disease BEFREE VEGF, Flt1, and Flk1 can be considered as indicators of the malignancy potential of diffusely infiltrating astrocytomas. 11908876 2001
CUI: C0004114
Disease: Astrocytoma
Astrocytoma 		0.050 Biomarker disease BEFREE Vascular endothelial growth factor (VEGF), through activation of its endothelial receptors VEGFR-1 and VEGFR-2, is an important positive modulator of tumor angiogenesis and edema in solid tumors such as malignant astrocytomas. 11058875 2000