KDR, kinase insert domain receptor, 3791

N. diseases: 623; N. variants: 23
Disease: Hemangioblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0206734
Disease: Hemangioblastoma
Hemangioblastoma 		0.010 Biomarker disease BEFREE However, the finding of dramatic up-regulation of vascular endothelial growth factor (VEGF), a potent endothelial cell growth factor with vascular permeability-inducing activity, in stromal cells and the corresponding receptors, VEGFR-1 and VEGFR-2, in tumor endothelial cells suggests that angiogenesis and cyst formation in hemangioblastomas may be regulated by this signaling pathway via a paracrine mechanism. 8930647 1996