KDR, kinase insert domain receptor, 3791

N. diseases: 623; N. variants: 23
Disease: Progressive Neoplastic Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0677932
Disease: Progressive Neoplastic Disease
Progressive Neoplastic Disease 		0.020 AlteredExpression phenotype BEFREE Patients with high VEGFR2 expression showed a better initial response (partial response, 40%; stable disease, 20%; progressive disease, 40%) than patients with low expression did (partial response, 0%; stable disease, 58.3%; progressive disease, 41.7%; P=.052). pRCC with high VEGFR2 expression seems to be associated with a better initial response to targeted drug therapy and a better prognostic outcome. 27989785 2017
CUI: C0677932
Disease: Progressive Neoplastic Disease
Progressive Neoplastic Disease 		0.020 Biomarker phenotype BEFREE The patient was initially treated with sorafenib, an inhibitor of VEGFR2, and developed progressive disease. 27160228 2016