ACAT1, acetyl-CoA acetyltransferase 1, 38

N. diseases: 98; N. variants: 4
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023364
Disease: Leptospirosis
Leptospirosis
0.100 Biomarker disease BEFREE Seroprevalence of leptospirosis in human was 27.84% (95% CI: 13.22-22.47) and 19.71% (95% CI: 6.78-32.65%) based on ELISA and MAT, respectively. 31698052 2020
CUI: C0023364
Disease: Leptospirosis
Leptospirosis
0.100 Biomarker disease BEFREE Comparison of the ELISA assay with MAT for the detection of Leptospiral antibodies showed a positive correlation (r value 0.345, p < 0.05), and signified the diagnostic efficacy of rPI-PLC for the definitive diagnosis of the Leptospirosis. 30848449 2019
CUI: C0023364
Disease: Leptospirosis
Leptospirosis
0.100 Biomarker disease BEFREE This study verified the main Leptospira spp. serovars detected by MAT from serum of patients with suspicion of leptospirosis from 2008 to 2012 in Minas Gerais State. 28365095 2018
CUI: C0023364
Disease: Leptospirosis
Leptospirosis
0.100 Biomarker disease BEFREE Two horses were positive on urine PCR for leptospirosis (shedding prevalence 1%), yet only one had a high reciprocal MAT titer of ≥ 800. 30372498 2018
CUI: C0023364
Disease: Leptospirosis
Leptospirosis
0.100 Biomarker disease BEFREE Seroepidemiology of leptospirosis in Guilan province, northern Iran: comparison between MAT and IgM-ELISA techniques. 31825912 2018
CUI: C0023364
Disease: Leptospirosis
Leptospirosis
0.100 Biomarker disease BEFREE We showed that leptospirosis significantly affects humans in Vanuatu: 12 cases were confirmed by real-time PCR on acute blood samples (n = 5) or by high serology titers evidencing a recent infection (MAT titer ≥800 or ELISA≥18 Units, n = 7). 29864127 2018
CUI: C0023364
Disease: Leptospirosis
Leptospirosis
0.100 Biomarker disease BEFREE Serums were screened by ELISA at Institut Pasteur de Côte d'Ivoire and confirmed by MAT in the National Reference Centre for leptospirosis in Institut Pasteur in Paris. 30128667 2018
CUI: C0023364
Disease: Leptospirosis
Leptospirosis
0.100 Biomarker disease BEFREE Patients were confirmed as leptospirosis (n = 65) and non-leptospirosis (n = 30) by the Patoc - MAT. 27707560 2016
CUI: C0023364
Disease: Leptospirosis
Leptospirosis
0.100 Biomarker disease BEFREE ELISA using Hap1/lipL 32-derived synthetic peptide PP is an earlier serological diagnosis of human leptospirosis than MAT. 19307019 2010
CUI: C0023364
Disease: Leptospirosis
Leptospirosis
0.100 Biomarker disease BEFREE Our cLigA based-serology has a high potential for early diagnosis of leptospirosis especially when the culture and MAT results are not yet available. 18079011 2008
CUI: C0023364
Disease: Leptospirosis
Leptospirosis
0.100 Biomarker disease BEFREE Isolation was rare from humans (2/45 Leptospira isolates from 881 febrile patients sampled), but high titers of MAT antibodies against "Leptospira licerasiae" serovar Varillal were common (30%) among patients fulfilling serological criteria for acute leptospirosis in the Iquitos region, and uncommon (7%) elsewhere in Peru. 18382606 2008
CUI: C0023364
Disease: Leptospirosis
Leptospirosis
0.100 Biomarker disease BEFREE The methods in hand for diagnosis of leptospirosis like culture, ELISA and MAT only help to confirm the disease, and are of little value in early detection. 15928441 2005