Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0409974
Disease: Lupus Erythematosus
Lupus Erythematosus
0.040 Biomarker disease BEFREE This mechanism appears to switch off the downstream events leading to secretion of pathogenic autoantibodies, thus explaining the highly promising results obtained in clinical trials of P140 (Lupuzor) for the treatment of lupus. 29499102 2018
CUI: C0409974
Disease: Lupus Erythematosus
Lupus Erythematosus
0.040 Biomarker disease BEFREE In vitro, P140 acts directly on a particular form of autophagy called chaperone-mediated autophagy, which seems to be hyperactivated in certain subsets of lymphocytes in lupus and in other autoinflammatory settings. 30219390 2018
CUI: C0409974
Disease: Lupus Erythematosus
Lupus Erythematosus
0.040 Biomarker disease BEFREE The investigation of killer cell immunoglobulin-like receptor genotyping in patients with systemic lupus erytematosus and systemic sclerosis. 26960450 2016
CUI: C0409974
Disease: Lupus Erythematosus
Lupus Erythematosus
0.040 GeneticVariation disease BEFREE Association of killer cell immunoglobulin-like receptor genotypes with vascular arterial events and anticardiolipin antibodies in patients with lupus. 18755860 2008