Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085281
Disease: Addictive Behavior
Addictive Behavior
0.010 Biomarker phenotype BEFREE Three tyrosine kinase inhibitors (TKIs) with KIT inhibitory activity - imatinib, sunitinib, and regorafenib - are approved to treat advanced GIST and have successfully exploited this addiction to KIT oncogenic signaling, demonstrating remarkable activity in a disease that historically had no successful systemic therapy options. 28478525 2017