KLRB1, killer cell lectin like receptor B1, 3820

N. diseases: 71; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 Biomarker group BEFREE CD161-expressing immune cells are found at the vicinity of these structures, with a global enrichment of NSCLC tumors in CD161<sup>+</sup> CD4<sup>+</sup> and CD8<sup>+</sup> T cells as compared to normal distant lung and peripheral blood. 29721382 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 Biomarker group BEFREE Importantly, NKR-2 targeted tumour cells and tumour neovasculature and the local tumour immunosuppressive microenvironment and this mechanism of action of NKR-2 was established in the absence of preconditioning. 29133316 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 Biomarker group BEFREE Tumor inflammatory infiltrate was assessed using immunohistologic staining (CD8 and CD161) and enzyme-linked immunosorbent assay (interferon-gamma). 18453976 2008