KNG1, kininogen 1, 3827

N. diseases: 279; N. variants: 24
Disease: Diabetic Retinopathy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy 		0.030 Biomarker disease BEFREE Our findings suggest that activation of factor XII and kallikrein-kinin system combined with NET formation actively occur in patients with DR and circulating levels of DNA-histone complex, factor XIIa and HMWK can be potential biomarkers to estimate the risk of DR. Strategies against factor XII activation may be beneficial to inhibit DR. 31426112 2019
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy 		0.030 Biomarker disease BEFREE Bradykinin Type 1 Receptor - Inducible Nitric Oxide Synthase: A New Axis Implicated in Diabetic Retinopathy. 30983997 2019
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy 		0.030 Biomarker disease BEFREE However, the role of BK in DR retinal endothelial injury remains unclear. 31298304 2019