ARG1, arginase 1, 383

N. diseases: 273; N. variants: 47
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.040 AlteredExpression disease BEFREE Induced IL-35<sup>+</sup>Foxp3<sup>+</sup> cell numbers in the TU region of the lung of patients with NSCLC associated with ARG1 mRNA expression and with TTF-1<sup>+</sup>PD-L1<sup>+</sup> cells. 30956278 2019
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.040 Biomarker disease BEFREE The results demonstrated that puerarin inhibited tumor growth and tumor volumes in NSCLC xenograft model, increased M1 markers [CD197+, inducible nitric oxide synthase (iNOS)+, CD40+)] and reduced M2 markers (CD206+, Arg-1+ and CD163+). 28101568 2017
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.040 AlteredExpression disease BEFREE Arginase-1 mRNA expression correlates with myeloid-derived suppressor cell levels in peripheral blood of NSCLC patients. 23850196 2013
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.040 AlteredExpression disease BEFREE Patients with NSCLC had increased ARG1 plasma levels as compared to healthy controls. 19431148 2009