ARG1, arginase 1, 383

N. diseases: 273; N. variants: 47
Disease: Diabetes Mellitus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.130 GeneticVariation group GWASCAT Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program. 31451708 2019
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.130 Biomarker group BEFREE In conclusion, sequential activation of LOX-1, JNK, and L-arginine consuming enzyme arginase-I in diabetes elicits superoxide-dependent oxidative stress and impairs endothelial NO-mediated dilation in coronary arterioles. 31015037 2019
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.130 Biomarker group BEFREE Serum exosomes mediate delivery of arginase 1 as a novel mechanism for endothelial dysfunction in diabetes. 29967177 2018
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.130 Biomarker group BEFREE Mechanisms of Diabetes-Induced Endothelial Cell Senescence: Role of Arginase 1. 29673160 2018