ARG2, arginase 2, 384

N. diseases: 103; N. variants: 4
Disease: Impaired glucose tolerance ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0271650
Disease: Impaired glucose tolerance
Impaired glucose tolerance 		0.020 Biomarker phenotype BEFREE Here we identify arginase 2 (Arg2) as a fasting-induced hepatocyte factor that protects against hepatic and peripheral fat accumulation, hepatic inflammatory responses, and insulin and glucose intolerance in obese murine models. 30962478 2019
CUI: C0271650
Disease: Impaired glucose tolerance
Impaired glucose tolerance 		0.020 AlteredExpression phenotype BEFREE Semi-quantitative reverse transcription polymerase chain reaction (RT-PCR) analysis revealed decreased expression of CXCR4 and β2 integrin and increased expression of arginase II in IGT subjects. 25303939 2015