KRT5, keratin 5, 3852

N. diseases: 203; N. variants: 58
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.030 AlteredExpression disease BEFREE We investigated mRNA expression of KRT5 and KRT20 and its predictive value in stage pT1 bladder cancer. 28074276 2017
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.030 GeneticVariation disease BEFREE The immunohistochemical expressions of only two markers, luminal (GATA3) and basal (KRT5/6), were sufficient to identify the molecular subtypes of bladder cancer with over 90% accuracy. 27612592 2016
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.030 Biomarker disease BEFREE To establish a role for insulin-like growth factor-1 (IGF-1) in bladder cancer susceptibility, we tested the effect of p-cresidine, a potent bladder carcinogen, in transgenic (TG) mice with human IGF-1 expression in the bladder driven by the bovine keratin 5 promoter (referred to as BK5.IGF-1 TG mice). 19415693 2009