RHOA, ras homolog family member A, 387

N. diseases: 193; N. variants: 16
Disease: Colonic Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.030 AlteredExpression group BEFREE In mice, RHOA inactivation contributes to colon cancer metastasis and reduced RHOA levels were observed at metastatic sites compared with primary human colon tumours. 25413277 2014
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.030 AlteredExpression group LHGDN RhoA mediates cyclooxygenase-2 signaling to disrupt the formation of adherens junctions and increase cell motility. 17178865 2006
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.030 AlteredExpression group BEFREE In all eight lung tumors examined, RHOA RNA levels were decreased relative to the level in normal surrounding tissue, whereas RHOA expression was decreased in only two of six colon tumors. 8039707 1994