|
Platelet Count measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
Protein measurement
|
0.100 |
GeneticVariation
|
group |
GWASDB |
A genome-wide association study of circulating galectin-3.
|
23056639 |
2012 |
|
Malignant Neoplasms
|
0.030 |
Biomarker
|
group |
BEFREE |
A greater understanding of the mechanisms of TBP-2 could produce potential new targets for the treatment of diseases, including cancer and diabetes, cardiovascular disease, and cataracts.
|
29854083 |
2018 |
|
Primary malignant neoplasm
|
0.030 |
Biomarker
|
group |
BEFREE |
A greater understanding of the mechanisms of TBP-2 could produce potential new targets for the treatment of diseases, including cancer and diabetes, cardiovascular disease, and cataracts.
|
29854083 |
2018 |
|
Malignant Neoplasms
|
0.030 |
Biomarker
|
group |
BEFREE |
TXNIP (VDUP-1, TBP-2): a major redox regulator commonly suppressed in cancer by epigenetic mechanisms.
|
21964212 |
2011 |
|
Primary malignant neoplasm
|
0.030 |
Biomarker
|
group |
BEFREE |
TXNIP (VDUP-1, TBP-2): a major redox regulator commonly suppressed in cancer by epigenetic mechanisms.
|
21964212 |
2011 |
|
Malignant Neoplasms
|
0.030 |
AlteredExpression
|
group |
BEFREE |
Here, we show that HDAC1 increases the resistance of cancer cells to oxidative stress by negatively regulating the expression of thioredoxin binding protein 2 (TBP-2).
|
19351825 |
2009 |
|
Primary malignant neoplasm
|
0.030 |
AlteredExpression
|
group |
BEFREE |
Here, we show that HDAC1 increases the resistance of cancer cells to oxidative stress by negatively regulating the expression of thioredoxin binding protein 2 (TBP-2).
|
19351825 |
2009 |
|
Diabetes
|
0.020 |
Biomarker
|
disease |
BEFREE |
A greater understanding of the mechanisms of TBP-2 could produce potential new targets for the treatment of diseases, including cancer and diabetes, cardiovascular disease, and cataracts.
|
29854083 |
2018 |
|
Diabetes Mellitus
|
0.020 |
Biomarker
|
group |
BEFREE |
A greater understanding of the mechanisms of TBP-2 could produce potential new targets for the treatment of diseases, including cancer and diabetes, cardiovascular disease, and cataracts.
|
29854083 |
2018 |
|
Diabetes
|
0.020 |
Biomarker
|
disease |
BEFREE |
Thioredoxin and binding proteins (ASK1 and TBP2) appear to control apoptosis or metabolic states such as carbohydrate and lipid metabolism related to diseases such as diabetes and atherosclerosis.
|
17115886 |
2007 |
|
Diabetes Mellitus
|
0.020 |
Biomarker
|
group |
BEFREE |
Thioredoxin and binding proteins (ASK1 and TBP2) appear to control apoptosis or metabolic states such as carbohydrate and lipid metabolism related to diseases such as diabetes and atherosclerosis.
|
17115886 |
2007 |
|
Cataract
|
0.010 |
Biomarker
|
disease |
BEFREE |
A greater understanding of the mechanisms of TBP-2 could produce potential new targets for the treatment of diseases, including cancer and diabetes, cardiovascular disease, and cataracts.
|
29854083 |
2018 |
|
Bilateral cataracts (disorder)
|
0.010 |
Biomarker
|
disease |
BEFREE |
A greater understanding of the mechanisms of TBP-2 could produce potential new targets for the treatment of diseases, including cancer and diabetes, cardiovascular disease, and cataracts.
|
29854083 |
2018 |
|
Premature Menopause
|
0.010 |
Biomarker
|
disease |
BEFREE |
TBP2 gene may not be associated with primary ovarian insufficiency.
|
27642674 |
2016 |
|
Ovarian Failure, Premature
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our study indicates that the TBP2 gene is not responsible for idiopathic POI in the Chinese Han population.
|
27642674 |
2016 |
|
Fibroid Tumor
|
0.010 |
Biomarker
|
disease |
BEFREE |
The mRNA level of (thioredoxin-1-binding protein) TBP-2 in leiomyomas was not altered when compared with the matched adjacent myometrium.
|
24130091 |
2014 |
|
Uterine Fibroids
|
0.010 |
Biomarker
|
group |
BEFREE |
The mRNA level of (thioredoxin-1-binding protein) TBP-2 in leiomyomas was not altered when compared with the matched adjacent myometrium.
|
24130091 |
2014 |
|
Neoplasms
|
0.010 |
AlteredExpression
|
group |
BEFREE |
The histone deacetylase (HDAC) inhibitor suberoylanilide hydroxamic acid (SAHA) elevated expression of the tumor-suppressor thioredoxin-binding protein 2 (TBP2), which subsequently enhanced the JAB1-TBP2 interaction and abolished the pre-S(2) mutant LHBS-induced degradation of p27(Kip1), which, in turn, recovered the normal cell cycle checkpoint.
|
23172669 |
2013 |
|
Endometriosis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
However, TBP-2 mRNA levels in the endometrium were lower, and the TRX to TBP-2 ratio was higher in patients with endometriosis than in the control group.
|
20172870 |
2010 |
|
Metabolic Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
Trx 1 and TBP-2 play crucial roles in pathophysiological mechanisms in metabolic disorders, cancer and inflammation.
|
20435060 |
2010 |
|
Osteosarcoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
These data suggest that ETS1 is involved in CD437-induced TBP2 mRNA expression in human osteosarcoma MG-63 cells.
|
19932085 |
2010 |
|
Osteosarcoma of bone
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
These data suggest that ETS1 is involved in CD437-induced TBP2 mRNA expression in human osteosarcoma MG-63 cells.
|
19932085 |
2010 |
|
Childhood Osteosarcoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
These data suggest that ETS1 is involved in CD437-induced TBP2 mRNA expression in human osteosarcoma MG-63 cells.
|
19932085 |
2010 |
|
Malignant tumor of colon
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, high levels of RFP expression correlated with down-regulation of TBP-2 in human colon cancers and were associated with poor clinical outcome.
|
19351825 |
2009 |