LIN28B, lin-28 homolog B, 389421

N. diseases: 126; N. variants: 24
Disease: Malignant neoplasm of lung ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.060 Biomarker disease BEFREE MiR-563 plays a tumor suppressive role in lung cancer progression via targeting oncogenic LIN28B. 31766078 2020
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.060 AlteredExpression disease BEFREE LIN28B expression is associated with tumor initiation, progression, resistance, and poor outcome in several solid cancers, including lung cancer. 29503447 2018
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.060 Biomarker disease BEFREE Our finding indicates that H19 depresses miR-196b to elevate LIN28B, resulting in accelerating cell proliferation in lung cancer. 29950144 2018
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.060 Biomarker disease BEFREE miR-203 enhances let-7 biogenesis by targeting LIN28B to suppress tumor growth in lung cancer. 28218277 2017
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.060 AlteredExpression disease BEFREE These results suggest the modulation of miR-4458/Lin28B expression offers a potential therapeutic strategy for lung cancer. 28603287 2017
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.060 Biomarker disease BEFREE Functional studies demonstrated that the stemness properties of LIN28B-expressing human breast and lung cancer cells were enhanced by IKKβ, whereas loss of LIN28B abolished stemness properties in these settings. 25744721 2015