LAG3, lymphocyte activating 3, 3902

N. diseases: 154; N. variants: 3
Disease: Myocarditis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027059
Disease: Myocarditis
Myocarditis 		0.010 Biomarker disease BEFREE Studies in mice have established that genetic deficiencies of checkpoint molecules, including PD-1, PD-L1, CTLA-4, and lymphocyte activation gene-3, result in enhanced risk of autoimmune T cell-mediated myocarditis and increased pathogenicity of heart antigen-specific effector T cells. 30721928 2019