NUDT19, nudix hydrolase 19, 390916

N. diseases: 3; N. variants: 3
Disease: CRANIOOSTEOARTHROPATHY ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2678439
Disease: CRANIOOSTEOARTHROPATHY
CRANIOOSTEOARTHROPATHY 		0.010 Biomarker disease BEFREE Two mammalian Nudix hydrolases, Nudt19 and Nudt7, degrade CoA <i>in vitro</i> Nudt19 and Nudt7 possess conserved Nudix and CoA signature sequences and specifically hydrolyze the diphosphate bond of free CoA and acyl-CoAs to form 3',5'-ADP and 4'-(acyl)phosphopantetheine. 29378847 2018