LAMC1, laminin subunit gamma 1, 3915

N. diseases: 57; N. variants: 17
Disease: Chromosome 21 monosomy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0795875
Disease: Chromosome 21 monosomy
Chromosome 21 monosomy 		0.010 AlteredExpression disease BEFREE Trisomy 21 embryos showed significant up-regulation of markers of cell differentiation (Cadherin-5 (CDH5) and Laminin subunit gamma-1 (LAMC1)), whereas monosomy 21 blastocysts showed higher expression of genes reported to be expressed in undifferentiated cells (Gamma-Aminobutyric Acid Type-A Receptor Beta3 Subunit (GABRB3) and GDF3). 28369516 2017