LAMC1, laminin subunit gamma 1, 3915

N. diseases: 57; N. variants: 17
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0877015
Disease: Pelvic Organ Prolapse
Pelvic Organ Prolapse
0.030 GeneticVariation disease BEFREE Comprehensive analysis of LAMC1 genetic variants in advanced pelvic organ prolapse. 22342894 2012
CUI: C0877015
Disease: Pelvic Organ Prolapse
Pelvic Organ Prolapse
0.030 GeneticVariation disease BEFREE While significant differences were identified between AA and Caucasian women, no associations were found between any LAMC1 gene variant and advanced POP. 20223449 2010
CUI: C0877015
Disease: Pelvic Organ Prolapse
Pelvic Organ Prolapse
0.030 GeneticVariation disease BEFREE Altogether these data suggest that a polymorphism in the promoter of LAMC1 may increase the susceptibility to early-onset pelvic organ prolapse. 17021862 2007