LEP, leptin, 3952

N. diseases: 931; N. variants: 15
Disease: Cerebral Infarction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction 		0.020 Biomarker disease BEFREE The present review outlines the discovery of leptin and discusses its association with cerebral ischemia/reperfusion. 30988703 2019
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction 		0.020 Biomarker disease BEFREE Based on these results, leptin may regulate mitochondrial respiratory chain enzymatic activities via mitochondria-targeted STAT3 to reduce ROS production and protect brain tissues from mitochondrial oxidative stress during cerebral ischemia. 30632310 2019