LEP, leptin, 3952

N. diseases: 931; N. variants: 15
Disease: Polyuria ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032617
Disease: Polyuria
Polyuria 		0.310 Biomarker phenotype BEFREE Although hexamethonium attenuated leptin's effect on HR, it failed to impair leptin's ability to restore euglycemia or to prevent the polyuria or increased water intake in STZ-diabetic rats. 27923809 2017
CUI: C0032617
Disease: Polyuria
Polyuria 		0.310 Biomarker phenotype CTD_human Oral administration of Nitraria retusa ethanolic extract enhances hepatic lipid metabolism in db/db mice model 'BKS.Cg-Dock7(m)+/+ Lepr(db/)J' through the modulation of lipogenesis-lipolysis balance. 25086370 2014