LEP, leptin, 3952

N. diseases: 931; N. variants: 15
Disease: Epileptic Seizures ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4317109
Disease: Epileptic Seizures
Epileptic Seizures 		0.310 Biomarker phenotype BEFREE The reduction of the levels of the pro-inflammatory cytokines TNF-α, IL-1β, and IL-6 caused by leptin, ghrelin, and NPY shows that these peptides may have anti-inflammatory effects in epileptic seizures. 27522536 2017
CUI: C4317109
Disease: Epileptic Seizures
Epileptic Seizures 		0.310 Therapeutic phenotype CTD_human Leptin-mediated cell survival signaling in hippocampal neurons mediated by JAK STAT3 and mitochondrial stabilization. 17993459 2008