LEPR, leptin receptor, 3953

N. diseases: 416; N. variants: 57
Disease: Malignant neoplasm of mouth ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth 		0.020 GeneticVariation group BEFREE These results suggest that the genetic polymorphism of LEP -2548 G/A (rs7799039), LEPR K109R (rs1137100), and LEPR rs1137101" genes_norm="3953">Q223R (rs1137101) were not associated to the susceptibility of oral cancer; SNP in LEP -2548 G/A showed a poor clinicopathological development of oral cancer; population without tobacco consumption and with polymorphic LEP -2548 G/A gene may significantly increase the risk to have oral cancer. 31021458 2019
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth 		0.020 GeneticVariation group BEFREE Association of leptin -2548G/A and leptin receptor Q223R polymorphisms with increased risk for oral cancer. 18855010 2009